REFERENCES
-
Aparicio, J. F., Colina, A. J., Ceballos, E. & Martin, J. F. (1999)
The Biosynthetic Gene Cluster for the 26-Membered ring Polyene Macrolide
Pimaricin. J. Biol. Chem. 274, 10133-10139.
-
Aparicio, J. F., Fouces, R., Mendes, M. V., Olivera, N. & Martin, J.
F. (2000). A complex multienzyme system encoded by five polyketide synthase
genes is involved in the biosynthesis of the 26-membered polyene macrolide
pimaricin in Streptomyces natalensis. Chem. Biol. 7, 895-905.
-
August, P. R., Tang, L., Yoon, Y. J., Ning, S., Muller, R. & Yu, T.
W. et al. (1998). Biosynthesis of the ansamycin antibiotic rifamycin, deductions
from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis
mediterranei S699. Chem. Biol. 5, 69-79.
-
Bevitt, D. J., Cortes, J., Haydock, S. F. & Leadlay, P. F. (1992).
6-Deoxyerythronolide-B synthase 2 from Saccharpolyspora erythraea. Cloning
of the structural gene, sequence analysis and inferred domain structure
of the multifunctional enzyme. Eur. J. Biochem. 204, 39-49.
-
Brauteset, T., Sekurova, O. N., Stella, H., Ellingsen, T. E., Valla, S.,
Strlm, A. R., & Zotchev, S. B. (2000). Biosynthesis of the polyene
antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis
of the gene cluster and deduction of the biosynthetic pathway. Chem. Biol.
7, 395-403.
-
Caffrey, P., Lynch, S., Flood, E., Finnan, S. & Oliynyk, M. (2001).
Amphotericin biosynthesis in Sterptomyces nodosus: deductions from analysis
of polyketide synthase and late genes. Chem. Biol. 8, 713-723.
-
Cortes, J., Haydock, S. F. & Bevitt, D. J. (1997). An unusually large
multifuctional polypeptide in the erythromycin-producing PKS of Saccharopolyspora
erythraea. Nature. 348, 176-8.
-
Floss, H. G. & Yu, T. W. (1999). Lessons from the rifamycin biosynthetic
gene cluster. Curr Opin Chem Biol. 3, 592-7. Review.
-
Gaitatzis, N., Silakowski, B., Kunze, B. Nordsiek, G., Blocker, H., Hofle,
G. & Muller, R. (2002). The biosynthesis of the aromatic myxobacterial
electron transport inhibitor stigmatellin is directed by a novel type of
modular polyketide synthase. J. Biol. Chem. 277, 13082-13090.
-
Ikeda, H., Nonomiya, T., Usami, M., Ohta, T. & Omura, S. (1999). Organisation
of the biosynthetic gene cluster for the polyketide antihelmintic macrolide
avermectin in Streptomyces avermitilis. Proc. Natl. Acad. Sci. USA 96,
9509-9514.
-
Kakavas, S. J., Katz, L. & Stassi, D. (1997). Identification and Characterization
of the niddamycin polyketide synthase genes from Streptomyces caelestis.
J. Bact. 179, 7515-7522.
-
Molnar, I., Schupp, T., Ono, M., Zirkle, R. E., Milnamow, M. & Ligon,
J. M. et al. (2000). The biosynthetic gene cluster for the microtubule-stabilizing
agents epothilones A and B from Sorangium cellulosum So ce90. Chem. Biol.
7, 97-109.
-
Schupp, T., Toupet, C., Cluzel, B., Neff, S., Hill, S., Beck, J. J. &
Ligon, J. M. (1995). A Sorangium cellulosum (myxobacterium) gene cluster
for biosynthesis of macrolide antibiotic soraphen A: cloning, characterization,
and homology to polyketide synthase genes from actinomycetes. J. Bact.
3673-3679.
-
Schwecke, T., Aparicio, J. F., Molnar, I., Konig, A., Khaw, L. E. &
Haydock, S. et al. (1995). The biosynthetic gene cluster for the polyketide
immunosuppresant rapamycin. Proc. Natl. Acad. Sci. USA 92, 7839-7843.
-
Silakowski, B., Nordsiek, G., Kunze, B., Blocker, H. & Muller, R. (2001).
Novel features in a combined Polyketide synthase/ non-ribosomal peptide
synthetase: The myxalamid biosynthetic gene cluster of the myxobacterium
Stigmatella aurantiaca Sga15. Chem. Biol. 8, 59-69.
-
Silakowski, B., Schairer, H. U., Ehret, H., Kunze, B. & Nordsiek, G.
et al. (1999). New lessons for combinatorial biosynthesis from myxobacteria.
The myxothiazol biosynthetic gene cluster of Stigmatella aurantiaca DW4/3-1.
J. Biol. Chem. 274, 37391-37399.
-
Tang, Li, Yoon, Y. J., Choi, C. Y. & Hutchinson, C. R. (1998). Characterization
of the enzymatic domains in the modular polyketide synthase involved in
rifamycin B biosynthesis by Amycolatopsis mediterrannei. Gene. 216, 255
-265.
-
Tang, Li, Shah, S., Chung, L., Carney, J., Katz, L., Khosla, C. & Julien,
B. (2000). Cloning and heterologous expression of the epothilone gene cluster.
Science. 287, 640-642.
-
Thompson, B. N., Gould, S. J. & Loper, J. E. (1997). Identification
and sequence analysis of the genes encoding a polyketide synthase required
for pyoluteorin biosynthesis in Pseudomonas flourescens Pf-5. Gene. 204,
17-24.
-
Thompson, B. N., Chaney, N., Wing, J. S., Gould, S. J. & Loper, J.
E. (1999). Characterization of the Pyoluteorin Biosynthetic Gene Cluster
of Pseudomonas flourescens Pf-5. J. Bact. 2166-2174.
-
Volchegursky, Y., Hu, Z., Katz, L., McDaniel, R. (2000). Biosynthesis of
the anti-parasitic agent megalomycin: transformation of erythromycin to
megalomycin in Saccharopolyspora erythraea. Mol Microbiol. 37, 752-762.h
-
Wu, K., Chung, L., Revill, W. P., Katz, L. & Reeves, C. D. (2000).
The Fk520 gene cluster of Strptomycetes hygroscopiocus var. ascomyceticus
(ATCC 14891) contains genes for biosynthesis of unusual polyketide extender
units. Gene. 251, 81-90.
-
Waldron, C., Matsushima, P., Rosteck, P. R., Broughton, M. C., Crawford,
K. P., Turner, J. & Madduri, K. et al. (2001). Cloning and analysis
of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.
Chem. Biol. 8, 487-499.
-
Wilkinson, C. J., Frost, E. J., Staunton, J. & Leadlay, P. F. (2001).
Chain initiation on the soraphen producing modular polyketide synthase
from Sorangium cellulosum. Chem. Biol. 8, 1192-1208.